Destination X (2006) was a professional wrestling pay-per-view (PPV) event produced by Total Nonstop Action Wrestling (TNA), which took place on March 12, 2006 from the TNA Impact! Zone in Orlando, Florida. It was the second event under the Destination X chronology. Eight matches were featured on the event's card.

Jason Reso
Christian Cage

Montaque Brown
Monty Brown

Nuufolau Joel Seanoa
Samoa Joe

Allen Jones
AJ Styles

Daniel Covell
Christopher Daniels

Jeffrey Jarrett
Jeff Jarrett

Chris Parks
Abyss

Chris Harris
"Wildcat" Chris Harris

James Cox
"Cowboy" James Storm

Terry Gerin
Rhino

Ron Killings
Ron "The Truth" Killings

Mark LoMonaco
Brother Ray

WWF: Hardy Boyz - Leap of Faith
WWF: Hardy Boyz - Leap of Faith

AEW Women's Eliminator Tournament
AEW Women's Eliminator Tournament

The Unbreakable Bunch
The Unbreakable Bunch

NJPW Dominion 6.11 in Osaka-jo Hall
NJPW Dominion 6.11 in Osaka-jo Hall

WWE Money in the Bank 2017
WWE Money in the Bank 2017

AWA SuperClash IV
AWA SuperClash IV

TNA Victory Road 2004
TNA Victory Road 2004

WrestleMania 39: Saturday
WrestleMania 39: Saturday

WWE Backlash 2017
WWE Backlash 2017

TNA Turning Point 2004
TNA Turning Point 2004

Stardom in Korakuen 2025 Sep.
Stardom in Korakuen 2025 Sep.

TNA Hard To Kill 2024
TNA Hard To Kill 2024